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KMID : 1001920150580060554
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Journal of Korean Neurosurgical Society
2015 Volume.58 No. 6 p.554 ~ p.556
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Primary Intracranial Leptomeningeal Melanomatosis
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Kim Do-Hyoung
Choi Chan-Young
Lee Chae-Heuck
Joo Mee
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Abstract
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Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures.
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KEYWORD
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Primary, Melanoma, CNS, Subarachnoid hemorrhage, Leptomeninges
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